Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

CiteULike is a free service for managing and discovering scholarly references - click here to get started.

Sign In to gain access to subscriptions and/or personal tools.
The Journal of the Royal Society for the Promotion of Health
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Vig, S.
Right arrow Articles by Stacey-Clear, A.
Right arrow Search for Related Content
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Lessons to be learned: a case study approach Insulinoma presenting as a change in personality

Stella Vig, BSc, MB, BCh, FRCS

Department of Surgery, East Surrey Hospital, Redhill, Surrey RH1 5RH, England

Mark Lewis, MB, BS, MRCS

Department of Surgery, East Surrey Hospital, Redhill, Surrey RH1 5RH, England

Kenneth J. Foster, DM, FRCP

Department of Medicine, East Surrey Hospital, Redhill, Surrey RH1 SRH, England

Adam Stacey-Clear, BSc, MS, FRCS

Department of Surgery, East Surrey Hospital, Redhill, Surrey RH1 5RH, England

A 43-year-old man presented with attacks of altered behaviour over a short period of time; they were associated with episodes of hypoglycaemia. The clinical suspicion of insulinoma prompted investigations that quickly established serum insulin and C- peptide levels to be elevated at the times when blood glucose values were low A physical lesion was found in the head of the pancreas by means of computerised tomography and endo-duodenal ultra sound scan; an octreotide scan was nega tive. The patient underwent laparotomy and enucleation of a benign tumour, mea suring 2.6 cm in diameter, lying within the head of the pancreas; histological examina tion confirmed it to be an insulinoma. Post operatively, the patient's personality gradu ally became more normal and his fasting blood glucose concentrations returned to within normal limits. The diagnosis and management of insulinoma are discussed in the context of this clinical case; there is also reference to the protean clinical mani festations that may occur in this condition- and its differential diagnosis.

Key Words: Clinical presentation • diagnosis • hypoglycaemia • insulinoma • localisation • treatment

The Journal of the Royal Society for the Promotion of Health, Vol. 121, No. 1, 56-61 (2001)
DOI: 10.1177/146642400112100112
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?